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Search Results for " igf1 receptor "
Targets Recommended: IGF-1R

2

抑制剂 & 化合物

6

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T76810 Ganitumab

AMG 479

IGF-1R Tyrosine Kinase/Adaptors
Ganitumab (AMG 479) 是一种高效的1型胰岛素样生长因子受体 (IGF1R) 单克隆抗体。Ganitumab 在低浓度下识别与 IGF1R 结合,KD 值为0.22 nM,Ganitumab 对小鼠 IGF1R 与 IGF1IGF2 的相互作用有抑制作用。Ganitumab 可用于研究癌症。
T76746 Figitumumab

Figitumumab (CP-751871) 为一种高效对抗胰岛素样生长因子 1 受体 (IGF1R) 的全人单克隆抗体。通过阻断 IGF1IGF1R 的结合,其 IC50 值达到 1.8 nM。

化合物

Ganitumab
Cat.No: T76810
Synonym: AMG 479
Target: IGF-1R
Figitumumab
Cat.No: T76746
Synonym:
Target:
Cat. No. Product Name Species Expression System
TMPY-00834 IGF1R/CD221 Protein, Human, Recombinant (His)

IGF-I R,IGFR,IGFIR,IGF

Human HEK293 Cells
IGF1R/CD221 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 81 kDa and the accession number is P08069.
TMPY-04360 IGF1R/CD221 Protein, Human, Recombinant (His & GST)

JTK13,insulin-like growth factor 1 rec...

Human Baculovirus Insect Cells
IGF1R/CD221 Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 74.6 kDa and the accession number is P08069.
TMPY-06905 IGF1R/CD221 Protein, Human, Recombinant (His & Avi), Biotinylated

CD221,insulin-like growth factor 1 rec...

Human HEK293 Cells
IGF1R/CD221 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 106.14 kDa and the accession number is NP_000866.1.
TMPH-01536 ITGB4 Protein, Human, Recombinant (His & Myc)

Human E. coli
Integrin alpha-6/beta-4 is a receptor for laminin. Plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the regulation of keratinocyte polarity and motility. ITGA6:ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling. ITGA6:ITGB4 binds to IGF1 and this binding is essential for IGF1 signaling. ITGA6:ITGB4 binds to IGF2 and this binding is essential for IGF2 signaling.
TMPJ-00781 LR3-IGF-1 Protein, Mouse, Recombinant (His)

IGF1,insulin-like growth factor 1...

Mouse E. coli
Insulin-like growth factor I (IGF1) belongs to the family of insulin-like growth factors that are structurally homologous to proinsulin. Mouse IGF-I is synthesized as two precursor isoforms with alternate N- and C-terminal propeptides. These isoforms are differentially expressed by various tissues. Mature mouse IGF-I shares 94% and 99% aa sequence identity with human and rat IGF-I, respectively, and exhibits cross-species activity. It shares 60% aa sequence identity with mature mouse IGF-II. IG...
TMPY-02194 SOCS3 Protein, Human, Recombinant (His & Trx)

SOCS-3,SSI-3,ATOD4,Cish3,SSI3,suppressor of cytokine signali...

Human E. coli
Suppressor of cytokine signaling 3, also known as SOCS-3, Cytokine-inducible SH2 protein 3, CIS-3, STAT-induced STAT inhibitor 3, SOCS3 and CIS3, is a protein which is widely expressed with high expression in heart, placenta, skeletal muscle, peripheral blood leukocytes, fetal and adult lung, and fetal liver and kidney. SOCS3 / CIS3 contains one SH2 domain and one SOCS box domain. SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. ...

重组蛋白

IGF1R/CD221 Protein, Human, Recombinant (His)
Cat.No: TMPY-00834
Species: Human
Expression System: HEK293 Cells
IGF1R/CD221 Protein, Human, Recombinant (His & GST)
Cat.No: TMPY-04360
Species: Human
Expression System: Baculovirus Insect Cells
IGF1R/CD221 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-06905
Species: Human
Expression System: HEK293 Cells
ITGB4 Protein, Human, Recombinant (His & Myc)
Cat.No: TMPH-01536
Species: Human
Expression System: E. coli
LR3-IGF-1 Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-00781
Species: Mouse
Expression System: E. coli
SOCS3 Protein, Human, Recombinant (His & Trx)
Cat.No: TMPY-02194
Species: Human
Expression System: E. coli
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